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Shading indicates the density of the number of SNPs at a given position.Look to the bottom right, and you see the gene around which much of the paper hinges, .
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I said yesterday I would say a bit more about the new paper on rapid recent high altitude adaptation among the Tibetans when I’d read the paper. Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude: Residents of the Tibetan Plateau show heritable adaptations to extreme altitude.
We sequenced 50 exomes of ethnic Tibetans, encompassing coding sequences of 92% of human genes, with an average coverage of 18x per individual.
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Genes showing population-specific allele frequency changes, which represent strong candidates for altitude adaptation, were identified.
The strongest signal of natural selection came from endothelial Per-Arnt-Sim (PAS) domain protein 1 (EPAS1), a transcription factor involved in response to hypoxia.Nudist beaches were never so crowded with stunning forms as in this year! Here you will see everything that was hidden before!Watch the naked girls changing their clothes in front of you. If girl doesn't take her bra off on the beach, you still have the chance to see bare jiggling tits and even more.It’s an enormous outlier, with SNPs where Tibetans and Han differ a great deal.This is important in regards to looking for genes which may drive adaptation to higher altitudes; if you don’t have different genes then you don’t have different traits.They did use a large number of neutral markers though, so I’m not too worried about biases in their data set.